Effects of Transdermal Testosterone Tretment on Inflammatory Markers in Elderly Males
نویسندگان
چکیده
منابع مشابه
Pharmacokinetics of a new testosterone transdermal delivery system, TDS-testosterone in healthy males.
AIMS The Transdermal Delivery System (TDS) is a liquid formulation that can be applied to the skin via a metered pump spray to deliver drug to the systemic circulation. The aims of this study were to assess the ability of the TDS preparation to deliver testosterone systemically, and to characterize the pharmacokinetic profiles of the hormone in healthy males. METHODS An open label, comparativ...
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Objective Spinal cord injury (SCI) causes infertility in male patients through erectile dysfunction, ejaculatory dysfunction, semen and hormone abnormalities. Oxidative stress (OS) is involved in poor semen quality and subsequent infertility in males with SCI. The aim of this study is to examine the effects of SCI on the level of testosterone hormone. MaterialsAndMethods In this experimental st...
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BACKGROUND Testosterone deficiency is linked to low-grade inflammation in humans, but this condition is not replicated in an animal study. The current study aims at determining the effects of testosterone deficiency and its replacement on the circulating inflammatory cytokine level in orchidectomized male rats. METHODS Three-month-old Sprague-Dawley male rats (n = 18) were randomized equally ...
متن کاملTransdermal delivery of testosterone.
Male hypogonadism has been treated with exogenous testosterone since the 1930s. The early transdermal patches of testosterone became available in the 1980s with gel and solution preparations following subsequent decades. This review focusses on the skin permeation characteristics of testosterone, pharmacokinetics following application of transdermal formulations and formulations currently avail...
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ژورنال
عنوان ژورنال: Endocrine Practice
سال: 2014
ISSN: 1530-891X
DOI: 10.4158/ep13357.or